Prevalence of Parathyroid Carcinoma and Atypical Parathyroid Neoplasms in 153 Patients With Multiple Endocrine Neoplasia Type 1: Case Series and Literature Review
نویسندگان
چکیده
منابع مشابه
Parathyroid carcinoma in multiple endocrine neoplasia type 1. Case report and review of the literature.
Parathyroid carcinoma is an infrequent cause of primary hyperparathyroidism. Although hyperparathyroidism in multiple endocrine neoplasia 1 (MEN1) syndrome is the most common manifestation, parathyroid carcinoma is rare. We report a male patient who was diagnosed at 44 years of age with parathyroid carcinoma in the context of MEN1 syndrome coincident with a malignant gastrinoma and non-function...
متن کاملParathyroid Carcinoma: Case Report and Review of the Literatur
Parathyroid carcinoma is a rare cause of primary hyperparathyroidism and occurs in one percent of cases. Most of the patients at the time of diagnosis are young and the mean age is 40 year-old and occur with equal frequency in both sexes. In most series, serum calcium levels are ≽ 14 mg/dl and in half of them, a palpable cervical mass is evident. Clinical manifestations are maily due to hyperca...
متن کاملSupernumerary parathyroid glands in hyperparathyroidism associated with multiple endocrine neoplasia type 1.
OBJECTIVE To evaluate frequency, anatomic presentation, and quantities of supernumerary parathyroids glands in patients with primary hyperparathyroidism (HPT1) associated with multiple endocrine neoplasia type 1 (MEN1), as well as the importance of thymectomy, and the benefits of localizing examinations for those glands. METHODS Forty-one patients with hyperparathyroidism associated with MEN1...
متن کاملNonfunctional Metastatic Parathyroid Carcinoma in the Setting of Multiple Endocrine Neoplasia Type 2A Syndrome
Parathyroid carcinoma is a very rare malignancy. It has been associated with hyperparathyroidism-jaw tumour syndrome, familial isolated primary hyperparathyroidism, and multiple endocrine neoplasia type 1 (MEN-1) and 2A (MEN-2A) syndromes. We report a 54-year-old man with a MEN-2A which presents with a nonfunctional metastatic parathyroid carcinoma and a pheochromocytoma in the absence of medul...
متن کاملParathyroid carcinoma: a case series.
INTRODUCTION We present 3 patients with parathyroid carcinoma and describe their presentations, clinical profiles, and management. MATERIALS AND METHODS A case series review of medical records. RESULTS Two women and 1 man (age range, 32 to 57 years) had parathyroid cancer and primary hyperparathyroidism (PHPT). One patient presented with osteitis fibrosa, 1 with renal stone and a neck mass,...
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ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2020
ISSN: 1664-2392
DOI: 10.3389/fendo.2020.557050